2026 NFL Odds Week 1: Lines, Spreads For All 16 Games

Headlined by a Sept. 9 Super Bowl rematch between the Seahawks and Patriots, as well as the NFL’s first-ever game in Australia between the Rams and 49ers, Week 1 is absolutely loaded. Here are the lines for every Week 1 matchup at DraftKings Sportsbook as of Sept. 3. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports. WEDNESDAY, SEPT. 9 Patriots @ Seahawks Spread: Seahawks -3.5Moneyline: Seahawks -175, Patriots +145O/U: 44.5 THURSDAY, SEPT. 10 49ers @ Rams (Australia) Spread: Rams -3.5Moneyline: Rams -198, 49ers +164O/U: 48.5 SUNDAY, SEPT. 13 Saints @ Lions Spread: Lions -7Moneyline: Lions -298, Saints +240O/U: 49.5 Bears @ Panthers Spread: Bears -2.5Moneyline: Bears -155, Panthers +130O/U: 47.5 Ravens @ Colts Spread: Ravens -3.5Moneyline: Ravens -175, Colts +145O/U: 48.5 Falcons @ Steelers Spread: Steelers -3.5Moneyline: Steelers -185, Falcons +154O/U: 42.5 Browns @ Jaguars Spread: Jaguars -7.5Moneyline: Jaguars -395, Browns +310O/U: 40.5 Buccaneers @ Bengals Spread: Bengals -3.5Moneyline: Bengals -198, Buccaneers +164O/U: 50.5 Bills @ Texans Spread: Bills -1.5Moneyline: Bills -118, Texans -102O/U: 44.5 Jets @ Titans Spread: Titans -1.5Moneyline: Titans -130, Jets +110O/U: 38.5 Commanders @ Eagles Spread: Eagles -5.5Moneyline: Eagles -218, Commanders +180O/U: 45.5 Cardinals @ Chargers Spread: Chargers -10.5Moneyline: Chargers -550, Cardinals +410O/U: 46.5 Dolphins @ Raiders Spread: Raiders -3.5Moneyline: Raiders -198, Dolphins +164O/U: 40.5 Packers @ Vikings Spread: Vikings -1.5Moneyline: Vikings -118, Packers -102O/U: 45.5 Cowboys @ Giants Spread: Cowboys -2.5Moneyline: Cowboys -148, Giants +124O/U: 48.5 MONDAY, SEPT. 14 Broncos @ Chiefs Spread: Chiefs -3Moneyline: Chiefs -148, Broncos +124O/U: 42.5 Read More​Latest NFL News & Videos from FOX Sports nfl ​