2026 NFL Odds Week 5: Lines, Spreads, Results For All 15 Games

NFL Week 5 is just about here, and it kicks off with a Thursday tilt between the Buccaneers and Cowboys. The Panthers and Chiefs have the first byes of the season. Here are the lines for every Week 5 matchup at bet365 Sportsbook as of Oct. 6. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports. Spread: Cowboys -8.5Moneyline: Cowboys -455, Buccaneers +350O/U: 47.5 Spread: Jaguars -6.5Moneyline: Jaguars -285, Eagles +230O/U: 42.5 Spread: Bears -3Moneyline: Bears -148, Packers +124O/U: 45.5 Spread: Bengals -7Moneyline: Bengals -345, Dolphins +275O/U: 42.5 Spread: Jets -2.5Moneyline: Jets -130, Browns +110O/U: 39.5 Spread: Texans -6.5Moneyline: Texans -340, Titans +290O/U: 38.5 Spread: Steelers -2.5Moneyline: Steelers -135, Colts +114O/U: 44.5 Spread: Patriots -3.5Moneyline: Patriots -190, Raiders +160O/U: 45.5 Spread: Commanders -3Moneyline: Commanders -175, Giants +145O/U: 43.5 Spread: Vikings -1.5Moneyline: Vikings -125, Saints +105O/U: 42.5 Spread: Broncos -3.5Moneyline: Broncos -185, Chargers +155O/U: 42.5 Spread: Lions -4.5Moneyline: Lions -218, Cardinals +180O/U: 54.5 Spread: Seahawks -3Moneyline: Seahawks -148, 49ers +124O/U: 47.5 Spread: Falcons -3Moneyline: Falcons -155; Ravens +130O/U: 43.5 Spread: Rams -2.5Moneyline: Rams -142, Bills +120O/U: 53.5 Read More​Latest NFL News & Videos from FOX Sports nfl ​